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于磊

發布時間:2019-03-06 08:59:08  作者:本站編輯  來源:本站原創  瀏覽次數:

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于磊,女,198110月生,博士,副教授,碩士生導師,藥學院副院長(主持工作),生物制藥教研室主任。2004年畢業于沈陽藥科大學藥學專業,獲學士學位;2012年畢業于哈爾濱醫科大學藥理學專業,獲博士學位。2009年進修于美國佐治亞州立大學,主要從事離子通道在心血管張力調節機制中的作用等相關藥理學,以及生物制藥學方向的研究工作。

主持國家自然科學基金一項,省教育廳課題一項,省衛生廳課題一項。2008年獲黑龍江省科學與技術進步二等獎及省教育廳科學與技術進步一等獎,2009年獲黑龍江省科學與技術進步二等獎,2011年獲黑龍江省高??茖W技術一等獎及教育廳高等學??茖W研究優秀成果二等獎一項。共發表SCI收錄文章11篇。,

 

發表文章:

1. Yu L, Jin X, Cui N, Wu Y, Shi Z, Zhu D, Jiang C. Rosiglitazone selectively inhibits KATP channels by acting on the Kir6 subunit. Br J Pharmacol. 2012 Mar 6. doi: 10.1111/j.1476-5381.2012.01934.x.

2. Xin Jin*, Lei Yu* Shuang Zhang, Yang Wu, Zhenda Shi, Xianfeng Chen1, Yang Yang2, Xiaoli Zhang3 and Chun Jiang,* S-Glutathionylation underscores the modulation of the heteromeric Kir4.1-Kir5.1 channel in oxidative stress. J Physiol. 2012 Nov 1;590(Pt 21):5335-48.

3. Yu L*, Jin X*, Yang YCui NJiang C. Rosiglitazone inhibits vascular K(ATP) channels and coronary vasodilation produced by isoproterenol. Br J Pharmacol. 2011 Dec;164(8):2064-72. doi: 10.1111/j.1476-5381.2011.01539.x. (IF 4.4)

4. Yu L*, Yun L*, Zhaoping Q, Shulin Liu, Xu G, Daling Z. Cellular mechanisms and intracellular signaling pathways for the modulation of eNOS in pulmonary arteries by 15-HETE. Journal of Receptors and Signal Transduction. 2012 Apr;32(2):87-95. Epub 2012 Mar 6.

5. Wang Y, Yu L, Cui N, Jin X, Zhu D, Jiang C. Differential sensitivities of the vascular KATP channel to various PPAR activators Biochem Pharmacol. 2013 May 15;85(10):1495-503.

6. Yang Y, Li S, Konduru AS, Zhang S, Trower TC, Shi W, Cui N, Yu L, Wang Y, Zhu D, Jiang C. Prolonged exposure to methylglyoxal causes disruption of vascular KATP channel by mRNA instability. Am J Physiol Cell Physiol. 2012 Nov 15;303(10):C1045-54.

7. Liu Y, Ma C, Zhang Q, Yu L, Ma J, Zhang L, Hao X, Cao F, Wang L, Zhu D. The key role of transforming growth factor-beta receptor I and 15-lipoxygenase in hypoxia-induced proliferation of pulmonary artery smooth muscle cells. Int J Biochem Cell Biol. 2012 Jul;44(7):1184-202. Epub 2012 Apr 19. (IF 4.95)

8. Cui NZhang XTadepalli JSYu LGai HPetit JPamulapati RTJin XJiang C. Involvement of TRP channels in the CO? chemosensitivity of locus coeruleus neurons. J Neurophysiol. 2011 Jun;105(6):2791-801. Epub 2011 Mar 23. (IF 4.00)

9. Liu Y, Zhang J, Yu L, Cao F, Rao J, Li J, Jiang C, Falck JR, Jacobs ER, Zhu D: A soluble epoxide hydrolase inhibitor--8-HUDE increases pulmonary vasoconstriction through inhibition of K(ATP) channels. Pulm Pharmacol Ther. 2012 Feb;25(1):69-76. Epub 2011 Dec 3.(IF 2.09)

10. Jun Ma, Shujun Liang, Zhigang Wang, Lei Zhang, Jing Jiang, Jinhua Zheng, Lei Yu, Xiaodong Zheng, Ruifang Wang, Daling Zhu: ROCK pathway participates in the processes that 15-hydroxyeicosatetraenoic acid (15-HETE) mediated the pulmonary vascular remodeling induced by hypoxia in rat. Journal of Cellular Physiology. 2010 222(1): 82-94. (IF 3.87)

11. Wu ZH, Tang XB, Wang ZG, Ji HY, Yu L, Liu HW, Zhu DL : Preparation and characterization of monoclonal antibody against human carboxylesterases-II. Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi. 2007 Feb;23(2):148-51.




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地址:黑龍江省大慶市高新區新陽路39
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